Tetrahydrobiopterin for treating conditions associated with elevated phenylalanine levels

The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food for treating BH4-responsive disorders. Also disclosed are biopterin assays for measuring the amount of biopterin and metabolites of...

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Bibliographische Detailangaben
Hauptverfasser:	Castillo, Sianna, Foehr, Erik, Oppenheimer, Daniel I, Dorenbaum, Alejandro, Okhamafe, Augustus, Kostel, Paul John
Format:	Patent
Sprache:	eng ; lit
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food for treating BH4-responsive disorders. Also disclosed are biopterin assays for measuring the amount of biopterin and metabolites of biopterin in a sample.