PROCESS FOR THE PREPARATION OF 1-DESOXYNOJIRIMYCINE AND TIS N-DERIVATIVES

A process for preparing a 1-deoxynojirimycin of the formula in which R is hydrogen, optionally substituted alkyl or aralkyl, which comprises converting D-glucose to an aminosorbitol protecting the amino group of the aminosorbitol with an alkalinically detachable group to form the protected compound...

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Hauptverfasser: SCHRODER, THEO, DTUBBE, MATHIAS
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:A process for preparing a 1-deoxynojirimycin of the formula in which R is hydrogen, optionally substituted alkyl or aralkyl, which comprises converting D-glucose to an aminosorbitol protecting the amino group of the aminosorbitol with an alkalinically detachable group to form the protected compound of the formula in which X is an alkalinically detachable protective group, microbiologically oxidizing the protected compound to an oxidation product of the formula alkalinically splitting off the protective group X to form an aminosorbose of the formula and reducing the aminosorbose.