QUINAZOLINE DERIVATIVES

A compound of the formula: in which R and R are each hydrogen, halogen, lower alkoxy or halo(lower)alkyl, R is aryl or ar(lower)alkyl, both of which may have one or more suitable substituent(s), or heterocyclic(lower)alkyl, R is carboxy or protected carboxy, A is oxygen or sulfur atom, Y is carbonyl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BABA, YUKIHISA, NAMIKI, TAKAYUKI, HASHIMOTO, MASASHI, KASAHARA, CHIOYOSHI, SAWADA, KOJO, ITOH, YOSHIKUNI, OKU, TERUO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A compound of the formula: in which R and R are each hydrogen, halogen, lower alkoxy or halo(lower)alkyl, R is aryl or ar(lower)alkyl, both of which may have one or more suitable substituent(s), or heterocyclic(lower)alkyl, R is carboxy or protected carboxy, A is oxygen or sulfur atom, Y is carbonyl, thiocarbonyl or sulfonyl and Z is lower alkylene, and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them in admixture with pharmaceutically acceptable carriers.