ARYLHYDROXAMATES AND PREPARATION OF THEREOF

ARYLHYDROXAMATES AND PREPARATION OF THEREOF

Arylhydroxamates are provided having the structurewherein R1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, orwherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C1-C4 alkylamino or C1-C4- dialkylamino. R2 is hydrogen or lower alkyl; and R3 is C1-C20-alkyl or C3-C10-alkenyl,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KARANEWSKY DONALD S, HASLANGER MARTIN F
Format: Patent
Sprache:eng ; kor
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Arylhydroxamates are provided having the structurewherein R1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, orwherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C1-C4 alkylamino or C1-C4- dialkylamino. R2 is hydrogen or lower alkyl; and R3 is C1-C20-alkyl or C3-C10-alkenyl, aryl, arylalkyl, cycloalkyl, arylalkenyl, lower alkoxy, lower alkenyloxy, arylalkoxy or cycloalkyloxy. These compounds are useful as inhibitors of Δ5-lipoxygenase and as such are useful as antiallergy agents.