PROCESS FOR PREPARING PENEM ESTERS
Penem carboxyic acid esters of formula (I) are prepd. by esterifying a cpd. of formula (II) or its salt with a cpd. of formula RX in the presence of dimethylaminopyridine of dimethylformamide at 0-70 C. In the formulas, R is acetoxymethyl, pivaloxymethyl, methoxymethyl, methoxyethoxymethyl, phthalid...
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| creator | FOGLIO MAURIZIO SANFILIPPO AURORA FRANCESCHI GIOVANNI |
| description | Penem carboxyic acid esters of formula (I) are prepd. by esterifying a cpd. of formula (II) or its salt with a cpd. of formula RX in the presence of dimethylaminopyridine of dimethylformamide at 0-70 C. In the formulas, R is acetoxymethyl, pivaloxymethyl, methoxymethyl, methoxyethoxymethyl, phthalidyl, alpha-ethoxycarbonyloxyethyl, acetamidomethyl or benzamidomethyl group. The derivs. are useful as bactericidal agents. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR PREPARING PENEM ESTERS |
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