PROCESS FOR PREPARING CEPHALOSPORIN DERIVATIVES

PROCESS FOR PREPARING CEPHALOSPORIN DERIVATIVES

Cephalosporin derivs. of fromula (I) are prepd. by reacting a cpd. of formula (II) with a cpd. of formula (III). In the formulas, X is halogen; A is carbonic acid -protecting gp.; R1 is amino-protecting gp.; R is C1-6 alkyl; asterisk indicates (R), (S) or (RS)-form; n is 0 or 1; n' is 0-3; n2 i...

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Hauptverfasser: OKONOKI TSUNEO, MURAI YASUSHI, NISHIHATA KEN, SHIBAHARA SEIJI, KUTO TOSHIAKI, YOSHIDA TAKASHI
Format: Patent
Sprache:eng ; kor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Cephalosporin derivs. of fromula (I) are prepd. by reacting a cpd. of formula (II) with a cpd. of formula (III). In the formulas, X is halogen; A is carbonic acid -protecting gp.; R1 is amino-protecting gp.; R is C1-6 alkyl; asterisk indicates (R), (S) or (RS)-form; n is 0 or 1; n' is 0-3; n2 is 0-3. (I) are useful as antibiotics having a high bactericidal activity.