THE PROCESS OF PREPARING INDOLIZINE DERIVATIVES

Indolizine derivs. (I) were prepd. by reacting compd. (III) with N- chlorosuccinimide in dichloroethane at 0 - 25 C. Where R is C1-8 branched or straight chain alkyl radical, Ph radical, mono-F, -Cl, - Br, -Me or -Methoxy Ph radical, di-F, -Br-Ph radical, F, Cl, Br substd. Me-Ph radical ; X1 = Cl, B...

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Hauptverfasser: ROSSEELS, GILBERT, INION, HENRY
Format: Patent
Sprache:eng
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Zusammenfassung:Indolizine derivs. (I) were prepd. by reacting compd. (III) with N- chlorosuccinimide in dichloroethane at 0 - 25 C. Where R is C1-8 branched or straight chain alkyl radical, Ph radical, mono-F, -Cl, - Br, -Me or -Methoxy Ph radical, di-F, -Br-Ph radical, F, Cl, Br substd. Me-Ph radical ; X1 = Cl, Br, I ; R1 = Me, Et, n-pr, n-Bu radical ; n = integer of 2 - 6; A is R2 or R3 selected from (II); X2 = Cl, Br, I, Me, Methoxy ; X3 = Cl, Br, I, Me.