PROCESS FOR PREPARING -LACTAM-CONTAINING ANTIBACTERIAL AGENTS
Penems I (R=H, lower alkyl, 2,2,2-trichloroalkyl, benzyl, acetonyl, p-nitrobenzyl, p-methoxybenzyl, Ph, p-nitro-Ph, benzhydryl, acetoxymethyl, Me-CH-OCO2Et, CH2NHCOR2; R2=C1-C5 alkyl, aryl; Z=H, halo, OH, amino, carbamoyloxy, mercapto, pyridinium, OR3, OCOR3, NHCOR3, SR4; R3, R4 independently=lower...
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| creator | FOGLIO MAURIZIO SANFILIPPO AURORA ARCAMONE FEDERICO SCARAFILE COSIMO FRANCESCHI GIOVANNI |
| description | Penems I (R=H, lower alkyl, 2,2,2-trichloroalkyl, benzyl, acetonyl, p-nitrobenzyl, p-methoxybenzyl, Ph, p-nitro-Ph, benzhydryl, acetoxymethyl, Me-CH-OCO2Et, CH2NHCOR2; R2=C1-C5 alkyl, aryl; Z=H, halo, OH, amino, carbamoyloxy, mercapto, pyridinium, OR3, OCOR3, NHCOR3, SR4; R3, R4 independently=lower alkyl, aryl, heterocyclic ring; n=0, 1) were prepd. Thus, 2.0g methylpenicillinate S-oxide in 40mL toluene and 2.8g butandiol diacetate were refluxed for 24 hrs. to give 1.4g 4β-vinylthio - [1,2-diacetoxymethyl - 1 - [methoxycarbonyl-2-methyl-2-propenyl - azetidine-2-on-S-oxide. |
| format | Patent |
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Thus, 2.0g methylpenicillinate S-oxide in 40mL toluene and 2.8g butandiol diacetate were refluxed for 24 hrs. to give 1.4g 4β-vinylthio - [1,2-diacetoxymethyl - 1 - [methoxycarbonyl-2-methyl-2-propenyl - azetidine-2-on-S-oxide.</description><language>eng ; kor</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1984</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19840620&DB=EPODOC&CC=KR&NR=840000865B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19840620&DB=EPODOC&CC=KR&NR=840000865B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FOGLIO MAURIZIO</creatorcontrib><creatorcontrib>SANFILIPPO AURORA</creatorcontrib><creatorcontrib>ARCAMONE FEDERICO</creatorcontrib><creatorcontrib>SCARAFILE COSIMO</creatorcontrib><creatorcontrib>FRANCESCHI GIOVANNI</creatorcontrib><title>PROCESS FOR PREPARING -LACTAM-CONTAINING ANTIBACTERIAL AGENTS</title><description>Penems I (R=H, lower alkyl, 2,2,2-trichloroalkyl, benzyl, acetonyl, p-nitrobenzyl, p-methoxybenzyl, Ph, p-nitro-Ph, benzhydryl, acetoxymethyl, Me-CH-OCO2Et, CH2NHCOR2; R2=C1-C5 alkyl, aryl; Z=H, halo, OH, amino, carbamoyloxy, mercapto, pyridinium, OR3, OCOR3, NHCOR3, SR4; R3, R4 independently=lower alkyl, aryl, heterocyclic ring; n=0, 1) were prepd. Thus, 2.0g methylpenicillinate S-oxide in 40mL toluene and 2.8g butandiol diacetate were refluxed for 24 hrs. to give 1.4g 4β-vinylthio - [1,2-diacetoxymethyl - 1 - [methoxycarbonyl-2-methyl-2-propenyl - azetidine-2-on-S-oxide.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1984</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLANCPJ3dg0OVnDzD1IICHINcAzy9HNX0PVxdA5x9NV19vcLcfT0Awk5-oV4OgFFXYM8HX0UHN1d_UKCeRhY0xJzilN5oTQ3g7Kba4izh25qQX58anFBYnJqXmpJvHeQhYkBEFiYmTo5GRoTpwoA3M0q3w</recordid><startdate>19840620</startdate><enddate>19840620</enddate><creator>FOGLIO MAURIZIO</creator><creator>SANFILIPPO AURORA</creator><creator>ARCAMONE FEDERICO</creator><creator>SCARAFILE COSIMO</creator><creator>FRANCESCHI GIOVANNI</creator><scope>EVB</scope></search><sort><creationdate>19840620</creationdate><title>PROCESS FOR PREPARING -LACTAM-CONTAINING ANTIBACTERIAL AGENTS</title><author>FOGLIO MAURIZIO ; SANFILIPPO AURORA ; ARCAMONE FEDERICO ; SCARAFILE COSIMO ; FRANCESCHI GIOVANNI</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_KR840000865BB13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; kor</language><creationdate>1984</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FOGLIO MAURIZIO</creatorcontrib><creatorcontrib>SANFILIPPO AURORA</creatorcontrib><creatorcontrib>ARCAMONE FEDERICO</creatorcontrib><creatorcontrib>SCARAFILE COSIMO</creatorcontrib><creatorcontrib>FRANCESCHI GIOVANNI</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FOGLIO MAURIZIO</au><au>SANFILIPPO AURORA</au><au>ARCAMONE FEDERICO</au><au>SCARAFILE COSIMO</au><au>FRANCESCHI GIOVANNI</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR PREPARING -LACTAM-CONTAINING ANTIBACTERIAL AGENTS</title><date>1984-06-20</date><risdate>1984</risdate><abstract>Penems I (R=H, lower alkyl, 2,2,2-trichloroalkyl, benzyl, acetonyl, p-nitrobenzyl, p-methoxybenzyl, Ph, p-nitro-Ph, benzhydryl, acetoxymethyl, Me-CH-OCO2Et, CH2NHCOR2; R2=C1-C5 alkyl, aryl; Z=H, halo, OH, amino, carbamoyloxy, mercapto, pyridinium, OR3, OCOR3, NHCOR3, SR4; R3, R4 independently=lower alkyl, aryl, heterocyclic ring; n=0, 1) were prepd. Thus, 2.0g methylpenicillinate S-oxide in 40mL toluene and 2.8g butandiol diacetate were refluxed for 24 hrs. to give 1.4g 4β-vinylthio - [1,2-diacetoxymethyl - 1 - [methoxycarbonyl-2-methyl-2-propenyl - azetidine-2-on-S-oxide.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR PREPARING -LACTAM-CONTAINING ANTIBACTERIAL AGENTS |
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