PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS
Celphalosporins (II, R1 = protected aminl; R2 = H, protective group; R3 = H, lower alkyl, alkylthio, alkoxy; Z = S) were prepd. by hydrolysis of III. Thus, 0.35 g (6R, 7R)-3-phosphono-carbamoyloxy-methyl-7- Z-2-(fur-2-yl)-2-methoxy-imino-acetamido ceph-3-em-4-carboxylic acid was treated at 40 C for...
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creator | LAING STUART BRUCE HUMBER DAVID CEDRIC WEINGARTEN GORDON GAD |
description | Celphalosporins (II, R1 = protected aminl; R2 = H, protective group; R3 = H, lower alkyl, alkylthio, alkoxy; Z = S) were prepd. by hydrolysis of III. Thus, 0.35 g (6R, 7R)-3-phosphono-carbamoyloxy-methyl-7- Z-2-(fur-2-yl)-2-methoxy-imino-acetamido ceph-3-em-4-carboxylic acid was treated at 40 C for 5 hr, room temp 16 hr, 40 C 6 hr, 20 C 16 hr in the mixed solution of 4 ml H2O and 1 ml dioxane to give (6R, 7R)-3-carbamoyloxymethyl-7- Z-2-(fur-2-yl)-2-methoxy-iminoacetamido ceph-3-em-4-carboxylic acid. |
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Thus, 0.35 g (6R, 7R)-3-phosphono-carbamoyloxy-methyl-7- Z-2-(fur-2-yl)-2-methoxy-imino-acetamido ceph-3-em-4-carboxylic acid was treated at 40 C for 5 hr, room temp 16 hr, 40 C 6 hr, 20 C 16 hr in the mixed solution of 4 ml H2O and 1 ml dioxane to give (6R, 7R)-3-carbamoyloxymethyl-7- Z-2-(fur-2-yl)-2-methoxy-iminoacetamido ceph-3-em-4-carboxylic acid.</description><language>eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS ; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC ; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY ; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS ; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE</subject><creationdate>1983</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19830329&DB=EPODOC&CC=KR&NR=830000686A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19830329&DB=EPODOC&CC=KR&NR=830000686A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LAING STUART BRUCE</creatorcontrib><creatorcontrib>HUMBER DAVID CEDRIC</creatorcontrib><creatorcontrib>WEINGARTEN GORDON GAD</creatorcontrib><title>PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS</title><description>Celphalosporins (II, R1 = protected aminl; R2 = H, protective group; R3 = H, lower alkyl, alkylthio, alkoxy; Z = S) were prepd. by hydrolysis of III. 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Thus, 0.35 g (6R, 7R)-3-phosphono-carbamoyloxy-methyl-7- Z-2-(fur-2-yl)-2-methoxy-imino-acetamido ceph-3-em-4-carboxylic acid was treated at 40 C for 5 hr, room temp 16 hr, 40 C 6 hr, 20 C 16 hr in the mixed solution of 4 ml H2O and 1 ml dioxane to give (6R, 7R)-3-carbamoyloxymethyl-7- Z-2-(fur-2-yl)-2-methoxy-iminoacetamido ceph-3-em-4-carboxylic acid.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE |
title | PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS |
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