PROCESS FOR PREPARING CEPHALOSPORIN DERIVATIVES

Cephalosporins(I; R1 = H, lower alkyl; R2 = H, OH; R3 = OH, alkanoyloxy; R4 = H, methoxy; R6 = 5 membered heterocycle; Y = H, protecting group) were prepd. by the reaction of II and III. Thus, 0.57 g 7-[D(-)-α-[3-(3,4-dihydroxybenzoyl)-3-methyl-1-ureido -α-phenylacetamido -3-acetoxymethyl-3-cepehm-4...

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Bibliographische Detailangaben
Hauptverfasser:	OOI NOBUHIRO, AOKI BUNYA, SHINOZAKI TEIZO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE
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Beschreibung
Zusammenfassung:	Cephalosporins(I; R1 = H, lower alkyl; R2 = H, OH; R3 = OH, alkanoyloxy; R4 = H, methoxy; R6 = 5 membered heterocycle; Y = H, protecting group) were prepd. by the reaction of II and III. Thus, 0.57 g 7-[D(-)-α-[3-(3,4-dihydroxybenzoyl)-3-methyl-1-ureido -α-phenylacetamido -3-acetoxymethyl-3-cepehm-4-carboxylic acid and 0.13 g 5-methyl-2-mercapto-1,3,4-thia-diazole were reacted at 45-55 C for 24 hr to give I.