PROCESS FOR PREPARING -CARBOXY BENZYL ACETOAMIDO PENICILLANIC SALTS

Title compds. I; M = Na, K, organic amine (H NR3), R = C2-5 alkyl) were prepd. by the reaction of 6-aminopenicillanic acid with anhydride(IV) in organic solvent. Thus, anhydride(IV) was prepd. by the reaction of acylhalide and synthetic intermediate(III) obtained from phenylmalonic acid with N, N�...

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Bibliographische Detailangaben
Hauptverfasser: CHOI SEOUNG YOUNG, CHOI WON SHIK
Format: Patent
Sprache:eng
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Zusammenfassung:Title compds. I; M = Na, K, organic amine (H NR3), R = C2-5 alkyl) were prepd. by the reaction of 6-aminopenicillanic acid with anhydride(IV) in organic solvent. Thus, anhydride(IV) was prepd. by the reaction of acylhalide and synthetic intermediate(III) obtained from phenylmalonic acid with N, N' -bistrialkylsilylimidazolidinone (II), and anhydride(IV), R1,R2,R3 are same or not, C1-3 alkyl, R4 - R5R6R7C or C2H5O-, R5,R6R7 are same or not, C1-3 alkyl) was reacted with 6-aminopenicillanic acid in organic solvent to give I.