PROCESS OF MANUFACTURING PIPERAZINYL QUINAZOLINE

Piperazinyl quinazolines{I;R=H, methoxy, R2=C1-C5 alkenyl, benzoyl, furoyl, thenoyl, alkoxycarbonyl, C4-C5 alkenyloxycarbonyl or C4-C5 (2-hydroxyalkoxy) carbonyl}, useful as antihypertensive, were prepd. by treating aminobenzoic compd. [III; A=CN or-c(=NH)-x-R3 ; X=O or S R3=C1-C6 alkyl in inactive...

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description Piperazinyl quinazolines{I;R=H, methoxy, R2=C1-C5 alkenyl, benzoyl, furoyl, thenoyl, alkoxycarbonyl, C4-C5 alkenyloxycarbonyl or C4-C5 (2-hydroxyalkoxy) carbonyl}, useful as antihypertensive, were prepd. by treating aminobenzoic compd. [III; A=CN or-c(=NH)-x-R3 ; X=O or S R3=C1-C6 alkyl in inactive org. solvent as lower alkanol, ether, aromatic carbohydrate or pyridine.
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title PROCESS OF MANUFACTURING PIPERAZINYL QUINAZOLINE
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