PROCESS OF MANUFACTURING PIPERAZINYL QUINAZOLINE

PROCESS OF MANUFACTURING PIPERAZINYL QUINAZOLINE

Piperazinyl quinazolines{I;R=H, methoxy, R2=C1-C5 alkenyl, benzoyl, furoyl, thenoyl, alkoxycarbonyl, C4-C5 alkenyloxycarbonyl or C4-C5 (2-hydroxyalkoxy) carbonyl}, useful as antihypertensive, were prepd. by treating aminobenzoic compd. [III; A=CN or-c(=NH)-x-R3 ; X=O or S R3=C1-C6 alkyl in inactive...

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1. Verfasser: HESS H J E
Format: Patent
Sprache:eng
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Zusammenfassung:Piperazinyl quinazolines{I;R=H, methoxy, R2=C1-C5 alkenyl, benzoyl, furoyl, thenoyl, alkoxycarbonyl, C4-C5 alkenyloxycarbonyl or C4-C5 (2-hydroxyalkoxy) carbonyl}, useful as antihypertensive, were prepd. by treating aminobenzoic compd. [III; A=CN or-c(=NH)-x-R3 ; X=O or S R3=C1-C6 alkyl in inactive org. solvent as lower alkanol, ether, aromatic carbohydrate or pyridine.