항-돌연변이 칼레티쿨린(CALR) 항체 및 이의 용도

항-mutant 칼레티쿨린(mutCALR) 항체가 개시되어 있다. 관련 핵산, 벡터, 세포, 키트 및 약제학적 조성물이 또한 개시되어 있다. 항-mutCALR 항체로 골수증식성 신생물을 치료하거나 진단하는 방법이 또한 개시되어 있다. Anti-mutant calreticulin (mutCALR) antibodies are disclosed. Also disclosed are related nucleic acids, vectors, cells, kits, and pharmaceutical compositions. Methods of...

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Bibliographische Detailangaben
Hauptverfasser:	NASTRI HORACIO G, ZHAO YONGHONG, ZHOU JING, STEWART SHAUN M, CELIK HAMZA, DELLER MARC C, MCQUIRTER LESLIE BROOKE EPLING, BUONPANE REBECCA A, MAYES PATRICK, LEI HSIANG TING, REIS EDIMARA S, WASS BRITTNEY MELISSA
Format:	Patent
Sprache:	kor
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
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Beschreibung
Zusammenfassung:	항-mutant 칼레티쿨린(mutCALR) 항체가 개시되어 있다. 관련 핵산, 벡터, 세포, 키트 및 약제학적 조성물이 또한 개시되어 있다. 항-mutCALR 항체로 골수증식성 신생물을 치료하거나 진단하는 방법이 또한 개시되어 있다. Anti-mutant calreticulin (mutCALR) antibodies are disclosed. Also disclosed are related nucleic acids, vectors, cells, kits, and pharmaceutical compositions. Methods of treating or diagnosing myeloproliferative neoplasms with the anti-mutCALR antibodies are also disclosed.