DUSP6 DUSP6 deficient stem cells and their use

The present invention relates to DUSP6-deficient stem cells and uses thereof, wherein the DUSP6 deficiency uses a CRISPR/Cas9 system, and the stem cells prepared in the present invention have improved survival rate and excellent differentiation ability, and thus can be applied to various treatment f...

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Bibliographische Detailangaben
Hauptverfasser:	IM YOUNGSAM, KIM YONG OU, YOO DAEHOON
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to DUSP6-deficient stem cells and uses thereof, wherein the DUSP6 deficiency uses a CRISPR/Cas9 system, and the stem cells prepared in the present invention have improved survival rate and excellent differentiation ability, and thus can be applied to various treatment fields. 본 발명은 DUSP6가 결핍된 줄기세포 및 이의 용도에 관한 것으로, 상기 DUSP6 결핍은 CRISPR/Cas9 시스템을 이용하며, 본 발명에서 제조된 줄기세포는 생존율 향상 및 우수한 분화능을 보유하고 있으므로, 다양한 치료 분야에 적용될 수 있다.