Double Strand Oligonucleotide Structure For Blood Brain Barrier Permeability and Composition For Preventing or Treating Neurological Disorder Comprising the Same

The present invention relates to a blood-brain barrier-penetrable double-stranded oligonucleotide structure and a composition for preventing or treating neurological diseases comprising the same, and to a double-stranded oligonucleotide structure conjugated via glucose linkers and a composition for...

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Bibliographische Detailangaben
Hauptverfasser:	KIM JANGSEON, PARK JUN HONG, LEE SAM YONG, PARK JUN YONG, PARK HAN OH, KIM JI YEOUNG, KO YOUNG HO
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a blood-brain barrier-penetrable double-stranded oligonucleotide structure and a composition for preventing or treating neurological diseases comprising the same, and to a double-stranded oligonucleotide structure conjugated via glucose linkers and a composition for preventing or treating neurological diseases comprising the same. 본 발명은 혈뇌 장벽 투과 가능한 이중가닥 올리고뉴클레오티드 구조체 및 이를 포함하는 신경학적 질환 예방 또는 치료용 조성물에 관한 것으로, 글루코스가 링커를 통해 접합된 이중가닥 올리고뉴클레오티드 구조체 및 이를 포함하는 신경학적 질환 예방 또는 치료용 조성물에 관한 것이다.