T Method for predicting the efficacy of treatment effects in glioblastoma by T cells

The present invention relates to a method for predicting the efficacy of a treatment effect of glioblastoma by T cells, which comprises a step of measuring the expression level of a poliovirus receptor (PVR) protein or a gene encoding the same from a biological sample. According to the present inven...

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Bibliographische Detailangaben
Hauptverfasser:	YUNKYUNG LEE, TAI GYU KIM, PARK SOON A, STEPHEN AHN, HAEYOUN CHOI
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a method for predicting the efficacy of a treatment effect of glioblastoma by T cells, which comprises a step of measuring the expression level of a poliovirus receptor (PVR) protein or a gene encoding the same from a biological sample. According to the present invention, since the expression level of a PVR protein or a gene encoding the same in the treatment of glioblastoma, the efficacy of a treatment effect by T cells can be predicted, and thus, the method can be useful for personalized glioblastoma treatment. 본 발명은 생물학적 시료로부터 PVR(poliovirus receptor) 단백질 또는 이를 코딩하는 유전자의 발현 수준을 측정하는 단계를 포함하는 T 세포에 의한 교모세포종 치료 효과의 유효성 예측 방법에 관한 것으로서, 교모세포종의 치료에 있어 PVR(poliovirus receptor) 단백질 또는 이를 코딩하는 유전자의 발현 수준을 측정함으로써 T 세포에 의한 치료 효과의 유효성을 예측할 수 있어, 개인 맞춤형 교모세포종의 치료에 유용하게 사용될 수 있다.