HLA-G HLA-G SPECIFIC ANTIBODIES AND USEDS THEREOF

The present invention relates to an antibody that specifically binds to HLA-G and uses thereof in treating cancer. The antibody binds to both HLA-G monomers and multimers and can prevent HLA-G from binding to its receptor, thereby being able to be usefully used for treating cancer. 본 발명은 HLA-G에 특이적으...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KIM CHAK HEE, KANG HYEON JU, YOON SUN HA, LEE JONG HYUN, YOON DA SEUL, JUNG SEUNG HEE, BYUN SUNG HYUN, KIM SOO YOUNG, PARK BUM CHAN, LEE CHUNG MIN, HA GYONG SIK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to an antibody that specifically binds to HLA-G and uses thereof in treating cancer. The antibody binds to both HLA-G monomers and multimers and can prevent HLA-G from binding to its receptor, thereby being able to be usefully used for treating cancer. 본 발명은 HLA-G에 특이적으로 결합하는 항체 및 이의 암 치료 용도에 관한 것으로 상기 항체는 HLA-G 단량체 및 다량체 모두에 결합하여 HLA-G가 이의 수용체에 결합하는 것을 방지할 수 있으므로 암 치료 용도로 유용하게 사용될 수 있다.