Novel Biomarkers for Diagnosing Ovarian Cancer

The present invention relates to a method for diagnosing ovarian cancer by measuring the expression level of genes or proteins involved in the development of ovarian cancer and a method for preventing or treating ovarian cancer by regulating the expression thereof. The present invention provides an...

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Bibliographische Detailangaben
Hauptverfasser:	YU MYEONG HEE, SE IK KIM, HUH SUNG HYUN, NOH DONG YOUNG, HAN SEUNG MAN, KANG UN BEOM, HYUN HOON CHUNG
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a method for diagnosing ovarian cancer by measuring the expression level of genes or proteins involved in the development of ovarian cancer and a method for preventing or treating ovarian cancer by regulating the expression thereof. The present invention provides an effective biomarker for ovarian cancer, especially high-grade serous ovarian cancer, and provides a method for predicting the onset of ovarian cancer early and with high reliability, by simultaneously suppressing or activating the expression of the relevant factors, to be able to be usefully used for efficient prevention or treatment of ovarian cancer. 본 발명은 난소암의 발병에 관여하는 유전자 또는 단백질의 발현량을 측정함으로써 난소암을 진단하는 방법 및 이들의 발현 조절을 통하여 난소암을 예방 또는 치료하는 방법에 관한 것이다. 본 발명은 난소암, 특히 고등급 장액성 난소암에 대한 유효한 바이오마커를 제공함으로써, 난소암의 발병을 조기에 높은 신뢰도로 예측할 수 있는 방법을 제공함과 동시에, 해당 인자들의 발현을 억제 또는 활성화함으로써 난소암의 효율적인 예방 또는 치료에 유용하게 이용될 수 있다.