Method for synthesizing bilirubin

The present invention relates to a method for synthesizing bilirubin. More specifically, the present invention relates to: bilirubin useful as a medicine by including the step of producing a compound represented by chemical formula 2 by dimerizing a compound represented by chemical formula 1 or coup...

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Bibliographische Detailangaben
Hauptverfasser: KIM MYUNG LIP, MA SANG HO, PARK KI SOO, JUN HEE GOO, KIM JIN BEOM, KIM DA EUN
Format: Patent
Sprache:eng ; kor
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Beschreibung
Zusammenfassung:The present invention relates to a method for synthesizing bilirubin. More specifically, the present invention relates to: bilirubin useful as a medicine by including the step of producing a compound represented by chemical formula 2 by dimerizing a compound represented by chemical formula 1 or coupling the same with the compound represented by chemical formula 3 and a compound represented by chemical formula 4; and a primary method of chemically synthesizing pegylated bilirubin. 본 발명은 빌리루빈의 합성 방법에 관한 것이다. 화학식 1로 표시되는 화합물을 다이머화 하거나 화학식 3으로 표시되는 화합물과 화학식 4로 표시되는 화합물과 커플링시켜, 화학식 2로 표시되는 화합물을 제조하는 단계를 포함함으로써 의약품 등으로 유용하게 활용되는 빌리루빈 및 페길화된 빌리루빈을 최초로 화학적으로 합성한 방법에 관한 것이다.