TRICYCLIC DERIVATIVE COMPOUNDS AND USE THEREOF

The present invention relates to a novel tricyclic derivative compound or a pharmaceutically acceptable salt thereof, and uses thereof. The present invention has excellent STAT3 inhibitory activity to exhibit an excellent inhibitory effect than known compounds currently in phase 3 clinical trials, t...

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Hauptverfasser: YOON MIJA, LEE DOHYUNG, KANG SEUNGHEE, KIM MISUN, LEE SANGHAK
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Sprache:eng ; kor
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creator YOON MIJA
LEE DOHYUNG
KANG SEUNGHEE
KIM MISUN
LEE SANGHAK
description The present invention relates to a novel tricyclic derivative compound or a pharmaceutically acceptable salt thereof, and uses thereof. The present invention has excellent STAT3 inhibitory activity to exhibit an excellent inhibitory effect than known compounds currently in phase 3 clinical trials, thereby being able to be used as a treatment for STAT3-related diseases. 본 발명은 신규 트리사이클릭 유도체 화합물 또는 이의 약제학적으로 허용 가능한 염 및 이의 용도에 관한 것으로, 우수한 STAT3 저해 활성을 갖는 것으로, 현재 임상 3상 진행중인 공지 화합물보다 우수한 억제효과를 나타내는 것으로 확인되어, STAT3 관련 질환의 치료제로 사용될 수 있다.
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subjects CHEMISTRY
FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title TRICYCLIC DERIVATIVE COMPOUNDS AND USE THEREOF
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