diHEP-DPA TH-DPAThe Docosahexaenoic Acid Derivatives diHEP-DPA and TH-DPA Synthesized via Recombinant Lipoxygenase Ameliorate Disturbances in Lipid Metabolism and Liver Inflammation in High Fat Diet-fed Mice

The present invention relates to the anti-obesity or anti-inflammatory activity of docosahexaenoic acid derivatives, diHEP-DPA and TH-DPA, synthesized through recombinant lipoxygenase. Studies on the interactions between SPMs and their target genes will provide additional insight into the anti-hyper...

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Hauptverfasser: JEONG WOO SEO, HACK SUN CHOI, JONG JAE YI
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to the anti-obesity or anti-inflammatory activity of docosahexaenoic acid derivatives, diHEP-DPA and TH-DPA, synthesized through recombinant lipoxygenase. Studies on the interactions between SPMs and their target genes will provide additional insight into the anti-hyperlipidemic effects of diHEP-DPA and TH-DPA. 본 발명은 재조합 리폭시게나아제를 통해 합성된 도코사헥사엔산 유도체, diHEP-DPA 및 TH-DPA의 항비만 또는 항염 활성에 관한 것이다.