Blood vessel graft having thrombus prevention function using electrospinning and manufacturing method thereof

The present invention relates to a synthetic polymer-natural polymer blood vessel graft having a thrombus prevention function using electrospinning and a manufacturing method thereof and, more specifically, to a blood vessel graft having a thrombus prevention function and a manufacturing method ther...

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Bibliographische Detailangaben
Hauptverfasser:	LEE GU HYUN, CHOI HYUN, LEE BONG SOO, KANG SEO HEE, KIM HYUNG TAE, MOON CHANG GI, KANG SUNG KWON, CHUNG DAEJOON
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OFARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES ORRIBBONS MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL NATURAL OR ARTIFICIAL THREADS OR FIBRES ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES SPINNING TEXTILES TREATMENT OR PROTECTION OF EYES OR EARS
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Beschreibung
Zusammenfassung:	The present invention relates to a synthetic polymer-natural polymer blood vessel graft having a thrombus prevention function using electrospinning and a manufacturing method thereof and, more specifically, to a blood vessel graft having a thrombus prevention function and a manufacturing method thereof, wherein the blood vessel graft has excellent biocompatibility and blood compatibility, and low neointima formation possibility by being manufactured with a technique of electrospinning a mixed polymer solution composed of a synthetic polymer, a natural polymer, a solvent, and an anti-thrombotic agent. The blood vessel graft according to the present invention is usefully used for hemodialysis, a palliative pediatric cardiac procedure, a peripheral vascular procedure, a coronary artery procedure, a venous procedure, a capillary procedure, and a non-vascular stent for the esophagus, the bile duct, the airway, the ureter, etc. 본 발명은 전기방사를 이용한 혈전 방지 기능을 갖는 합성고분자-천연고분자 혈관 그라프트 및 이의 제조 방법에 관한 것으로서, 더욱 상세하게는 합성고분자, 천연고분자, 용매 및 혈전방지제로 구성된 혼합 고분자 용액을 전기방사 기법을 이용하여 혈관 그라프트를 제조함으로써 생체 적합성 및 혈액 적합성이 뛰어나고, 신생 내막의 형성 가능성이 적으며 혈전 방지 기능을 갖는 혈관 그라프트 및 이의 제조 방법에 관한 것이다. 본 발명에 따른 혈관 그라프트는 혈액 투석용(hemodialysis), 소아 심장 수술용(palliative pediatric cardiac procedures), 말초 혈관 시술용, 관상동맥 시술용, 정맥 시술용, 모세혈관 시술용 및 식도, 담관, 기도 및 요관 등의 비혈관 스텐트의 커버용으로 유용하게 사용될 수 있다.