GENETICALLY ENGINEERED CELLS AND METHODS OF MAKING THE SAME

표적 핵산 서열의 편집 또는 표적 핵산 서열의 발현의 조절을 위한 CRISPR/CAS-관련 방법, 조성물 및 구성성분, 및 조작된 T 세포 또는 T 세포 전구체의 입양 전달을 포함하는 암 면역요법과 관련된 그의 적용법이 제공된다. Provided are CRIS PR/CAS-related methods, compositions and components for editing a target nucleic acid sequence, or modulating expression of a target nucleic acid sequenc...

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Bibliographische Detailangaben
Hauptverfasser:	SATHER BLYTHE, FRIEDLAND ARI E, NYE CHRIS, BUMCROT DAVID A, SALMON RUTH, JONES JON, WELSTEAD G. GRANT, RUBIO EUGENIO MARCO, MAEDER MORGAN L
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	표적 핵산 서열의 편집 또는 표적 핵산 서열의 발현의 조절을 위한 CRISPR/CAS-관련 방법, 조성물 및 구성성분, 및 조작된 T 세포 또는 T 세포 전구체의 입양 전달을 포함하는 암 면역요법과 관련된 그의 적용법이 제공된다. Provided are CRIS PR/CAS-related methods, compositions and components for editing a target nucleic acid sequence, or modulating expression of a target nucleic acid sequence, and applications thereof in connection with cancer immunotherapy comprising adoptive transfer of engineered T cells or T cell precursors.