C19 Composition for enhancing cancer treatment effect containing C19 and use thereof

The present invention relates to a pharmaceutical composition containing C19 (EMT inhibitor-1) as an active ingredient for enhancing the therapeutic effect of cancer, and uses thereof. Since the composition of the present invention can induce the activation of immunocytotherapies including natural k...

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Bibliographische Detailangaben
Hauptverfasser:	LEE YOUNG EUN, JANG MI HUE, YUK CHAE MIN
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmaceutical composition containing C19 (EMT inhibitor-1) as an active ingredient for enhancing the therapeutic effect of cancer, and uses thereof. Since the composition of the present invention can induce the activation of immunocytotherapies including natural killer cells or release of cancer cytotoxic molecules, and thus can improve penetration efficiency of a therapeutic agent by degrading/inhibiting the ECM, so that a cancer treatment effect can be enhanced by using the composition. 본 발명은 C19 (EMT inhibitor-1)를 유효성분으로 포함하는 암의 치료 효과 증진용 약학 조성물 및 이의 용도에 관한 것이다. 본 발명의 조성물은 자연살해 세포 등을 포함하는 면역세포치료제의 활성화 또는 암 세포독성 분자 방출을 유도하거나, ECM을 분해/억제하여 치료제의 침투 효율을 향상시킬 수 있는 바, 상기 조성물을 이용하여 암 치료 효과를 증진시킬 수 있다.