Method for Purification of Botulinum Toxin Complex with Improved Purification Yield

The present invention relates to a purification method of botulinum toxin with improved purification purity and yield. When the purification method of botulinum toxin of the present invention is used, the botulinum toxin can be purified in a very high yield. A purification method of a botulinum toxi...

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Bibliographische Detailangaben
Hauptverfasser: KIM CHUNG SEI, KIM MYUNG SEOB, SONG YOUNG JUN, SONG KWAN YOUNG
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a purification method of botulinum toxin with improved purification purity and yield. When the purification method of botulinum toxin of the present invention is used, the botulinum toxin can be purified in a very high yield. A purification method of a botulinum toxin complex of the present invention includes: (a) a step of preparing a culture solution of a botulinum toxin-producing strain; (b) a first purification step; and (c) a second purification step. 본 발명은 정제 순도 및 수율이 향상된 보툴리눔 독소 정제방법에 관한 것이다. 본 발명의 보툴리눔 독소 정제 방법을 이용하는 경우, 매우 높은 수율로 보툴리눔 독소를 정제할 수 있다.