TIMP Composition for treating bone disease comprising a TIMP protein inhibitor as an active ingredient

TIMP Composition for treating bone disease comprising a TIMP protein inhibitor as an active ingredient

The present invention relates to a composition for the treatment of osteogenic disorders comprising a TIMP protein inhibitor as an active ingredient. A TIMP inhibitor of the present invention promotes the differentiation of osteoblasts through the activation of β-catenin signaling, and thus can be u...

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Hauptverfasser: HAN YONG MAHN, CHOI JONG BIN
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Sprache:eng ; kor
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator HAN YONG MAHN
CHOI JONG BIN
description The present invention relates to a composition for the treatment of osteogenic disorders comprising a TIMP protein inhibitor as an active ingredient. A TIMP inhibitor of the present invention promotes the differentiation of osteoblasts through the activation of β-catenin signaling, and thus can be usefully used for the development of bone formation in osteogenic disorders such as Costello syndrome. 본 발명은 TIMP 단백질 억제제를 유효성분으로 포함하는 골 형성 장애 치료용 조성물에 관한 것으로, 본 발명의 TIMP 억제제는 β-카테닌 신호 전달의 활성화를 통해 조골세포 분화 촉진시켜, 코스텔로 증후군과 같은 골 형성 장애에서 골 형성 발달에 유용하게 사용될 수 있다.
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A TIMP inhibitor of the present invention promotes the differentiation of osteoblasts through the activation of β-catenin signaling, and thus can be usefully used for the development of bone formation in osteogenic disorders such as Costello syndrome. 본 발명은 TIMP 단백질 억제제를 유효성분으로 포함하는 골 형성 장애 치료용 조성물에 관한 것으로, 본 발명의 TIMP 억제제는 β-카테닌 신호 전달의 활성화를 통해 조골세포 분화 촉진시켜, 코스텔로 증후군과 같은 골 형성 장애에서 골 형성 발달에 유용하게 사용될 수 있다.</description><language>eng ; kor</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230104&amp;DB=EPODOC&amp;CC=KR&amp;NR=20230001109A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230104&amp;DB=EPODOC&amp;CC=KR&amp;NR=20230001109A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAN YONG MAHN</creatorcontrib><creatorcontrib>CHOI JONG BIN</creatorcontrib><title>TIMP Composition for treating bone disease comprising a TIMP protein inhibitor as an active ingredient</title><description>The present invention relates to a composition for the treatment of osteogenic disorders comprising a TIMP protein inhibitor as an active ingredient. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TIMP Composition for treating bone disease comprising a TIMP protein inhibitor as an active ingredient
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