Probiotics composition comprising lactic acid bacteria isolated from Kimchi and uses thereof

The present invention relates to a composition for preventing, alleviating, and treating a functional bowel disease, an inflammatory disease, and an allergic disease, which comprises as active ingredients a probiotic composition including lactic acid bacteria isolated from Kimchi, such as a Lactobac...

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Bibliographische Detailangaben
1. Verfasser:	HONG UNPYO
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	FODDER FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a composition for preventing, alleviating, and treating a functional bowel disease, an inflammatory disease, and an allergic disease, which comprises as active ingredients a probiotic composition including lactic acid bacteria isolated from Kimchi, such as a Lactobacillus curvatus RBK-1 strain, a Weissella cibaria RBK-2 strain, a Lactobacillus pentosus RBK-3 strain, a Lactobacillus brevis RBK-5 strain, a Lactobacillus plantarum RBK-8, and a Leuconostoc mesenteroides RBK-11 strain. The probiotic composition of the present invention increases the secretion of peptides that activate an enteric nervous system to activate the movement of an intestinal tract and alleviate constipation, so that the composition can be used as a material for improving a function of an intestinal tract. The composition of the present invention decreases the expression of inflammatory cytokines and suppresses the expression of inflammation-caused proteins to inhibit the secretion of an inflammation-mediated material, so that the composition can be used in treating an inflammatory disease. In addition, the composition of the present invention inhibits the secretion of materials that causes allergy and itching, reduces the expression of an inflammatory cytokine to alleviate itching, and increases the water content of the epidermis to be used in preventing and treating allergic diseases such as atopic dermatitis. 본 발명은 김치로부터 분리된 유산균인, 락토바실러스 커베터스 (Lactobacillus curvatus) RBK-1 균주, 와이셀라 시바리아 (Weissella cibaria) RBK-2 균주, 락토바실러스 펜토서스 (Lactobacillus pentosus) RBK-3 균주, 락토바실러스 브레비스 (Lactobacillus brevis) RBK-5 균주, 락토바실러스 플랜타룸 (Lactobacillus plantarum) RBK-8, 류코노스톡 메센테로이데스 (Leuconostoc mesenteroides) RBK-11 균주를 포함하는 프로바이오틱스 조성물을 유효성분으로 함유하는 긴으성 장질환, 염증성 질환 및 알레르기성 질환의 예방, 개선 및 치료용 조성물에 관한 것이다. 본 발명의 프로바이오틱스 조성물은 장 신경계 활성 펩티드 분비를 증가시켜 장관 운동을 활성화시키고 변비 증상을 개선시킴으로써 장관 기능 개선 소재로 이용될 수 있으며, 염증성 사이토카인의 발현을 감소시키고, 염증 유발 단백질의 발현을 억제하여 염증 매개 물질의 분비를 저해함으로써 염증성 질환의 치료에 이용될 수 있다. 아울러, 본 발명의 조성물은 알레르기 및 가려움증 유발 물질의 분비를 저해하고, 염증성 사이토카인의 발현을 감소시켜 가려움증을 완화하고, 표피의 수분함량을 증가시킴으로써 아토피 피부염과 같은 알레르기 질환의 예방 및 치료에 이용될 수 있다.