D- Pharmaceutical composition for preventing or treating epilepsy or seizure-related diseases comprising D-limonene as an active ingredient

The present invention relates to a pharmaceutical composition for preventing or treating epilepsy or seizure-related diseases. More specifically, the present invention relates to a pharmaceutical composition, a food composition, and health-functional food for preventing, alleviating, or treating epi...

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Bibliographische Detailangaben
Hauptverfasser:	SEO SO WOON, GU SUN MI, YUN JAE SUK, SONG YUN JEONG
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a pharmaceutical composition for preventing or treating epilepsy or seizure-related diseases. More specifically, the present invention relates to a pharmaceutical composition, a food composition, and health-functional food for preventing, alleviating, or treating epilepsy or seizure-related diseases comprising D-limonene as an active ingredient. D-limonene of the present invention can effectively alleviate convulsions when administered to an animal model with pentylenetetrazole (PTZ)-induced temporary convulsions or chronic convulsions. Accordingly, a composition of the present invention including D-limonene as an active ingredient can be usefully used for preventing or treating epilepsy or seizure-related diseases. Specifically, D-limonene is a natural material derived from peels of citrus fruits (Citrus unshiu Marcov), thereby being safe for the human body. 본 발명은 뇌전증 또는 발작 관련 질환의 예방 또는 치료용 약제학적 조성물에 관한 것으로, 더욱 자세하게는 D-리모넨을 유효성분으로 포함하는 뇌전증 또는 발작 관련 질환의 예방, 개선 또는 치료용 약제학적 조성물; 식품 조성물 및 건강기능식품에 관한 것이다. 본 발명의 D-리모넨은 PTZ(pentylenetetrazole)에 의해 유발되는 단발성 경련이나 만성 경련 동물모델에 투여하는 경우 경련을 효과적으로 완화시킬 수 있는바, 이를 유효성분으로 포함하는 본 발명의 조성물은 뇌전증 또는 발작 관련된 질환의 예방 또는 치료에 유용하게 사용될 수 있다. 특히, D-리모넨은 감귤류(Citrus unshiu Marcov) 과피에서 유래되는 천연 소재에 해당하는바, 인체에 안전한 이점을 갖는다.