Rf Rf Composition for improving muscle function comprising ginsenoside Rf ginsenoside composition comprising gincenoside Rf or mixture thereof as an effective component

Rf Rf Composition for improving muscle function comprising ginsenoside Rf ginsenoside composition comprising gincenoside Rf or mixture thereof as an effective component

According to the present invention, a ginsenoside Rf, a ginsenoside composition containing the ginsenoside Rf, or a mixture of any one or more thereof promotes the expression of Myosin Heavy Chain, which is a muscle differentiation marker, promotes AMPK phosphorylation which regulates energy homeost...

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Bibliographische Detailangaben
Hauptverfasser: LEE YOUNG CHUL, CHOI JAE WOONG, CHO CHANG WON, NHO EUL SONG, WON CHUL LIM, KIM KYUNG TACK, SHIN EUN JU, HONG HEE DO, LIM TAE GYU, RHEE YOUNGKYOUNG
Format: Patent
Sprache:eng ; kor
Schlagworte:
FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:According to the present invention, a ginsenoside Rf, a ginsenoside composition containing the ginsenoside Rf, or a mixture of any one or more thereof promotes the expression of Myosin Heavy Chain, which is a muscle differentiation marker, promotes AMPK phosphorylation which regulates energy homeostasis in a human body and plays an important role in skeletal muscle development and growth control, increases swimming duration in a forced swimming test in animal experiments to increase exercise capacity, strength, and muscle mass, and alleviates muscle atrophy, thereby being able to be used as a food composition for improving muscle function, a cosmetic composition for improving muscle function, a food composition for alleviating or preventing sarcopenia, or a pharmaceutical composition for treating or preventing sarcopenia. 본 발명의 진세노사이드 Rf, 진세노사이드 Rf를 포함하는 진세노사이드 조성물, 또는 이들 중 어느 하나 이상의 혼합물은 근육 분화 마커인 Myosin Heavy Chain 발현을 촉진시키고, 체내 에너지 항상성을 조절하고 골격근 발달 및 성장 조절에 중요한 역할을 수행하는 AMPK 인산화를 촉진시키며, 동물실험에서 강제유영시험에서 수영지속시간을 증가시켜 운동능력을 증가시키고, 근력을 증가시키고, 근육량을 증가시키며, 근위축을 완화시킬 수 있으므로, 근기능 개선용 식품 조성물, 근기능 개선용 화장료 조성물, 근감소증의 개선 또는 예방용 식품 조성물 또는 근감소증의 치료 또는 예방용 약학 조성물로 이용될 수 있다.