Heteroaryl-ethynyl derivative compounds and uses thereof

The present invention relates to a heteroaryl-ethynyl derivative compound and uses thereof. Since the heteroaryl-ethynyl derivative of the present invention exhibits excellent inhibitory activity against ABL, it can be usefully used as a therapeutic agent for the above ABL-related diseases. The pres...

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Bibliographische Detailangaben
Hauptverfasser:	HWANG DONGKEUN, PARK JINHEE, KIM KYUNEUN, CHOI HWANGEUN, LEE YEONGDEOK, KIM SUNGHWAN, IM HYERIM, KO EUNHWA
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a heteroaryl-ethynyl derivative compound and uses thereof. Since the heteroaryl-ethynyl derivative of the present invention exhibits excellent inhibitory activity against ABL, it can be usefully used as a therapeutic agent for the above ABL-related diseases. The present invention is completed by confirming that the heteroaryl-ethynyl derivative compound represented by chemical formula 1 inhibit the proliferation of ABL-activated cells. 본 발명은 헤테로아릴-에티닐 유도체 화합물 및 이의 용도에 관한 것이다. 본 발명의 헤테로아릴-에티닐 유도체는 ABL에 대해 우수한 억제 활성을 나타내므로, 상기 ABL 관련 질환의 치료제로 유용하게 사용될 수 있다.