Mesenchymal stem cells capable of improving tumor targeting and mass production of viruses

The present invention relates to a mesenchymal stem cell (MSC) for a virus carrier and virus propagation. More specifically, the present invention relates to the production of MSCs capable of controlling the timing of the production and release of viruses, thereby enabling improved tumor targeting a...

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Bibliographische Detailangaben
Hauptverfasser:	HONG JEONG A, SONG JAE JIN, CHOI SOO JIN, CHOI HYE JIN
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a mesenchymal stem cell (MSC) for a virus carrier and virus propagation. More specifically, the present invention relates to the production of MSCs capable of controlling the timing of the production and release of viruses, thereby enabling improved tumor targeting and mass production of viruses. In addition, the MSCs of the present invention can fundamentally block tumorigenicity, and controls the timing of the production and release of viruses so as to enable the viruses to be produced and released at a desired timing, thereby resulting in guaranteed safety and a maximized antitumor effect. 본 발명은 바이러스 전달체 및 바이러스 증식을 위한 중간엽 줄기세포로서, 종양 타겟팅 향상 및 바이러스 대량 생산을 가능하도록 바이러스 생산과 방출 시기 제어 가능한 중간엽 줄기세포 제작에 관한 것이다. 또한, 본 발명의 중간엽 줄기세포는 원천적으로 종양원성을 차단할 수 있으며, 원하는 시점에서 바이러스 생산과 방출이 가능하게 조절함으로써 안전성이 확보되며, 항종양 효과를 극대화시킬 수 있다.