Pyrimido-pyrimidinone Compounds and Pharmaceutical Composition Comprising the Same

The present invention relates to a pyrimido pyrimidinone compound having an effect of inhibiting PD-L1 expression, and a pharmaceutical composition comprising the same as an active ingredient. The pyrimido pyrimidinone compound of the present invention can be effectively used for the treatment or pr...

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Bibliographische Detailangaben
Hauptverfasser:	YOO HYEBIN, PARK SUNG JUN, YUN SI EUN, PARK SOJIN, PARK YOUNG JUN, YOON SUNG IL, SONG HYUNNAM, KIM JOON WOO
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a pyrimido pyrimidinone compound having an effect of inhibiting PD-L1 expression, and a pharmaceutical composition comprising the same as an active ingredient. The pyrimido pyrimidinone compound of the present invention can be effectively used for the treatment or prevention of cancer. One embodiment of the present invention relates to the pyrimido pyrimidinone compound represented by chemical formula I or the pharmaceutically acceptable salt thereof. 본 발명은 PD-L1 발현을 억제하는 효과를 가지는 피리미도 피리미디논 화합물 및 그를 유효성분으로 포함하는 약제학적 조성물에 관한 것이다. 본 발명의 피리미도 피리미디논 화합물은 암의 치료 또는 예방에 효과적으로 사용될 수 있다.