A composition for treating Bone disease comprising Exosome derived from epidural adipose tissue-derived mesenchymal stem cells

The present invention relates to a composition for preventing, alleviating, or treating bone diseases, comprising an epidural adipose mesenchymal stem cell-derived exosome. The composition of the present invention contains a large amount of anti-inflammatory factors, that is, cytokines, and contains...

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Bibliographische Detailangaben
Hauptverfasser:	LIM JU HYEON, KANG KYUNG KU, LEE GUN WOO, SEO MIN SOO, SUNG SOO EUN, LEE SI JOON, CHOI JOO HEE, KIM KIL SOO
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a composition for preventing, alleviating, or treating bone diseases, comprising an epidural adipose mesenchymal stem cell-derived exosome. The composition of the present invention contains a large amount of anti-inflammatory factors, that is, cytokines, and contains a low amount or no factors that can be involved in the differentiation of osteoclasts, and thus can be effectively used for preventing, alleviating, or treating bone diseases, inflammatory diseases, and the like. 본 발명은 경막외 지방 중간엽 줄기세포 유래 엑소좀을 포함하는 골 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 조성물은 항염증성인자 사이토카인을 다량 함유하고, 파골세포의 분화에 관여할 수 있는 인자들을 낮게 함유하거나 포함하지 않음으로써, 골질환, 염증질환 등의 예방, 개선 또는 치료에 유용하게 이용될 수 있다.