Stable pharmaceutical composition comprising esomeprazole and sodium bicarbonate
The present invention relates to a stable pharmaceutical composition containing omeprazole, an enantiomer or pharmaceutically acceptable salt thereof, and sodium hydrogen carbonate. Specifically, the present invention relates to a pharmaceutical composition having improved stability, which contains...
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| Format: | Patent |
| Sprache: | eng ; kor |
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| Zusammenfassung: | The present invention relates to a stable pharmaceutical composition containing omeprazole, an enantiomer or pharmaceutically acceptable salt thereof, and sodium hydrogen carbonate. Specifically, the present invention relates to a pharmaceutical composition having improved stability, which contains a low content of sodium hydrogen carbonate, has an excellent dissolution rate and bioavailability, and has reduced side effects caused by a high content of sodium hydrogen carbonate.
본 발명은 오메프라졸, 이의 거울상이성질체 또는 이의 약제학적으로 허용가능한 염, 및 탄산수소나트륨을 포함하는 안정한 약제학적 조성물에 관한 것이다. 구체적으로, 저함량의 탄산수소나트륨을 포함하며, 우수한 용출률 및 생체이용률을 갖고 고함량의 탄산수소나트륨으로 인해 발생하는 부작용을 감소시킨 개선된 안정성을 갖는 약제학적 조성물에 관한 것이다. |
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