Brain-damaged animal model with intra-septally delivered therapeutics treatment and preparation method thereof

The present invention relates to a brain-injured animal model in which a therapeutic agent is implanted into the nasal cavity so as to confirm the effectiveness of the brain-injured stem cell therapeutic agent and a method of manufacturing the same. The animal model according to the present inventio...

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Bibliographische Detailangaben
Hauptverfasser:	PARK CHAN HUM, LEE YOUNG JIN, LEE OK JOO, OLATUNJI AJITERU, KIM SOON HEE, LEE HAN NA, LEE JI SEUNG, HONG HEE SUN, SUH YE JI, MD TIPU SULTAN
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY CARE OF BIRDS, FISHES, INSECTS FISHING FORESTRY HUMAN NECESSITIES HUNTING NEW BREEDS OF ANIMALS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR TRAPPING
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Beschreibung
Zusammenfassung:	The present invention relates to a brain-injured animal model in which a therapeutic agent is implanted into the nasal cavity so as to confirm the effectiveness of the brain-injured stem cell therapeutic agent and a method of manufacturing the same. The animal model according to the present invention has the advantage of being able to confirm the paracrine effectiveness of the various brain injured stem cell therapeutic agents and is widely used when applying the brain injured stem cell therapeutic agents in actual clinical practice. 본 발명은 뇌손상 줄기세포 치료제의 효과를 확인할 수 있도록, 비강내로 치료제가 이식된 뇌손상 동물 모델 및 이의 제조방법에 관한 것으로, 본 발명에 따른 동물 모델은 다양한 뇌손상 줄기세포 치료제의 파라크라인 효능을 확인할 수 있을 뿐만 아니라, 실제 임상에서 뇌손상 줄기세포 치료제 적용 시에도 폭넓게 활용될 수 있는 장점이 존재한다.