3 E-N--1-4--1H--3- A novel E-N'-arylidene-1-4-chlorobenzyl-1H-indol-3-carbohydrazides as a procaspase-3 activator and an anticancer composition comprising the same as an active ingredient

3 E-N--1-4--1H--3- A novel E-N'-arylidene-1-4-chlorobenzyl-1H-indol-3-carbohydrazides as a procaspase-3 activator and an anticancer composition comprising the same as an active ingredient

The present invention relates to novel (E)-N-arylidene-1-(4-chlorobenzyl)-1H-indole-3-carbohydrazide as an activator of procaspase-3, and an anticancer composition comprising the same as an active component. 본 발명은 프로카스파제-3(procaspase-3)의 활성화제로서 신규한 (E)-N-아릴리덴-1-(4-클로로벤질)-1H-인돌-3-카보하이드라지드 및 이를 유효성분으로...

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Hauptverfasser: KIM YOUNG SOO, PARK EUN JAE, PHAN THI PHUONG DUNG, NGUYEN HAI NAM, DAO THI KIM OANH, HONG JIN TAE, PHUONG THAO TRAN, HAN SANG BAE
Format: Patent
Sprache:eng ; kor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to novel (E)-N-arylidene-1-(4-chlorobenzyl)-1H-indole-3-carbohydrazide as an activator of procaspase-3, and an anticancer composition comprising the same as an active component. 본 발명은 프로카스파제-3(procaspase-3)의 활성화제로서 신규한 (E)-N-아릴리덴-1-(4-클로로벤질)-1H-인돌-3-카보하이드라지드 및 이를 유효성분으로 포함하는 항암제 조성물에 관한 것이다.