1 New process for preparation of Edoxaban benzenesulfonate monohydrate
The present invention provides a novel method for manufacturing a crystalline form of edoxaban benzenesulfonate monohydrate. The manufacturing method according to the present invention has an effect of easily mass-producing edoxaban benzenesulfonate monohydrate in a high yield and low production cos...
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| Format: | Patent |
| Sprache: | eng ; kor |
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| Zusammenfassung: | The present invention provides a novel method for manufacturing a crystalline form of edoxaban benzenesulfonate monohydrate. The manufacturing method according to the present invention has an effect of easily mass-producing edoxaban benzenesulfonate monohydrate in a high yield and low production costs by manufacturing without separation of intermediate products from a starting reactant to the final product.
본 발명은 에독사반 벤젠술폰산염 1수화물 결정형의 신규한 제조방법을 제공한다. 본 발명에 따른 제조방법은 출발 반응물부터 최종 생성물까지 중간 생성물의 분리 없이 제조함으로써 에독사반 벤젠술폰산염 1 수화물을 고수율 및 낮은 생산단가로 용이하게 대량으로 생산할 수 있는 효과가 있다. |
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