ANIMAL MODEL FOR TRANSPLANTING HUMAN HEPATOCYTES AND A METHOD FOR SCREENING ANTI-VIRAL AGENT BY USING THE ANIMAL MODEL

The present invention relates to an animal model for human hepatocyte transplantation and an antiviral agent screening method using the same. The animal model for human hepatocyte transplantation of the present invention can become a humanized liver animal by transplanting human hepatocytes, so that...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	YU DAE YEUL, JEONG MI RA, YU EUN HYE, KIM KYUN HWAN, BAK IN SEON, LEE AH RAM, PARK EUN SOOK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS TRAPPING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to an animal model for human hepatocyte transplantation and an antiviral agent screening method using the same. The animal model for human hepatocyte transplantation of the present invention can become a humanized liver animal by transplanting human hepatocytes, so that human liver research can be easily performed. Specifically, the humanized liver animal derived from the animal model for human hepatocyte transplantation of the present invention can solve the problems accompanying a lot of cost and ethical problems that occur in the research and development of diseases that are expressed only in the livers of humans and chimpanzees. 본 발명은 인간 간세포 이식용 동물모델 및 이를 이용한 항바이러스제 스크리닝 방법에 관한 것이다. 본 발명의 인간 간세포 이식용 동물모델은 인간 간세포를 이식함으로써 인간화 간 동물이 될 수 있어 인간 간에 대한 연구가 용이하게 이루어질 수 있다. 구체적으로, 본 발명의 인간 간세포 이식용 동물모델로부터 유래된 인간화 간 동물은 종래 인간과 침팬지의 간에서만 발현되는 질병의 연구 개발에 있어 발생하는 많은 비용과 윤리적 문제를 수반하던 문제가 해소될 수 있다.