A NOVEL SYNTHETIC ROUTE FOR THE PRODUCTION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE AND THIAZOLE DERIVATE
The present invention relates to a method for producing an intermediate for production of edoxaban, and specifically, to a method for producing an intermediate for production of edoxaban, capable of obtaining, in high yield and purity, an optically active diamine derivative (Compound No. 7) and a th...
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| Format: | Patent |
| Sprache: | eng ; kor |
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| Zusammenfassung: | The present invention relates to a method for producing an intermediate for production of edoxaban, and specifically, to a method for producing an intermediate for production of edoxaban, capable of obtaining, in high yield and purity, an optically active diamine derivative (Compound No. 7) and a thiazole derivative (Compound No. 10), which are intermediates of the edoxaban, without use of high-pressure equipment and metal catalysts.
에독사반의 제조용 중간체의 제조 방법에 관한 것으로, 에독사반 중간체인 광학활성 다이아민 유도체(7번 화합물) 및 티아졸 유도체(10번 화합물)을 고압장비 및 금속 촉매를 사용하지 않고 높은 수율과 순도로 얻을 수 있는 에독사반의 제조용 중간체의 제조 방법에 관한 것이다. |
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