게놈을 조절하는 방법 및 조성물

표적 게놈을 조절하는 방법 및 조성물이 개시된다. Methods and compositions for modulating a target genome are disclosed. The composition may comprise a first RNA encoding a polypeptide comprising a retrotransposase reverse transcriptase domain and a retrotransposase endonuclease domain. The composition may also comprise...

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Bibliographische Detailangaben
Hauptverfasser:	LI DONGHUI, RUBENS JACOB ROSENBLUM, SALOMON WILLIAM EDWARD, CITORIK ROBERT JAMES, VON MALTZAHN GEOFFREY A, STEINBERG BARRETT ETHAN
Format:	Patent
Sprache:	kor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	표적 게놈을 조절하는 방법 및 조성물이 개시된다. Methods and compositions for modulating a target genome are disclosed. The composition may comprise a first RNA encoding a polypeptide comprising a retrotransposase reverse transcriptase domain and a retrotransposase endonuclease domain. The composition may also comprise a second RNA comprising a sequence that binds the polypeptide and a heterologous object sequence. The composition may insert the sequence of the heterologous object sequence into a target DNA.