Stabilized efinaconazole-containing pharmaceutical compositions comprising a combination of chelating agent antioxidant and acid

The present invention provides a pharmaceutical composition for topical administration in a form of an efinaconazole-containing solution, which comprises a specific combination of a chelating agent, an antioxidant, and an acid. The pharmaceutical composition of the present invention has excellent ph...

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Bibliographische Detailangaben
Hauptverfasser: KIM BEOM JOON, KOO KYO TAN
Format: Patent
Sprache:eng ; kor
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Beschreibung
Zusammenfassung:The present invention provides a pharmaceutical composition for topical administration in a form of an efinaconazole-containing solution, which comprises a specific combination of a chelating agent, an antioxidant, and an acid. The pharmaceutical composition of the present invention has excellent physicochemical stability. Therefore, the pharmaceutical composition of the present invention can be usefully used as a formulation for topical administration having excellent stability. 본 발명은 킬레이트화제, 항산화제, 및 산의 특정 조합을 포함하는 에피나코나졸-함유 용액 형태의 국소 투여용 약학 조성물을 제공한다. 본 발명의 약학 조성물은 우수한 물리화학적 안정성을 갖는다.