2 COMPOSITION KIT AND COMBINATION THERAPY FOR TREATING TYPE 2 DIABETES MELLITUS AND DIABETIC DYSLIPIDEMIA

The present invention relates to a combination therapy to efficiently treat type 2 diabetes and dyslipidemia in diabetic patients. More specifically, the present invention relates to a pharmaceutical composition, a kit, and a combination therapy, in which metformin as biguanide, glimepiride as sulfo...

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Bibliographische Detailangaben
Hauptverfasser:	LEE SUN, BANG KEUN SU, AHN JAE SOON, KIM SUNG HO, KIM JI YOON, KIM BO GYEONG, KIM SUNG WON, KIM SAM SIK
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to a combination therapy to efficiently treat type 2 diabetes and dyslipidemia in diabetic patients. More specifically, the present invention relates to a pharmaceutical composition, a kit, and a combination therapy, in which metformin as biguanide, glimepiride as sulfonylureas, and gemigliptin as a dipeptidyl peptidase IV inhibitor are used in combination to treat type 2 diabetes efficiently without side effects such as hypoglycaemia or changes in body weight and to reduce total cholesterol and low-density lipoprotein (LDL) cholesterol in blood, thereby efficiently treating dyslipidemia in diabetic patients. 본 발명은 제2형 당뇨병 및 당뇨 환자의 이상지질혈증을 효율적으로 치료하기 위한 병용 요법에 관한 것으로, 보다 상세하게는 비구아나이드제인 메트포르민, 설포닐요소제인 그리메피리드 및 디펩티딜 펩티다아제 IV 억제제인 제미글립틴을 병용하여 사용함으로써 저혈당증이나 체중 변화 같은 부작용이 없이 제2형 당뇨병을 효율적으로 치료하고, 혈중의 총 콜레스테롤 및 LDL 콜레스테롤을 감소시켜 당뇨 환자의 이상지질혈증을 효율적으로 치료하기 위한 약제학적 조성물, 키트 및 병용 요법에 관한 것이다.