IL-1 Extracellular vesicle isolated from recombinant cells comprising polynucleotide encoding IL-1 blockade as target protein and use thereof

The present invention relates to extracellular vesicles isolated from recombinant cells including a polynucleotide encoding an IL-1 inhibitor as a target protein, and use thereof. The extracellular vesicle loaded with the IL-1 inhibitor according to an aspect can be stably delivered when the IL-1 in...

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Bibliographische Detailangaben
Hauptverfasser: YUN JI AE, LIM SEON UNG, CHO SEUNG KEE, JEONG HYUN UK
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to extracellular vesicles isolated from recombinant cells including a polynucleotide encoding an IL-1 inhibitor as a target protein, and use thereof. The extracellular vesicle loaded with the IL-1 inhibitor according to an aspect can be stably delivered when the IL-1 inhibitor is loaded onto the extracellular vesicle and applied to the target site. 표적 단백질로서 IL-1 저해제를 코딩하는 폴리뉴클레오티드를 포함하는 재조합 세포로부터 분리된 세포외 소낭 및 그의 용도에 관한 것이다.