CRISPR/Cas9 Generation of canine dystrophinopathy model by nuclear transfer using CRISPR/Cas9-mediated somatic cells and th Use thereof

The present invention relates to a transgenic dog for a dystrophinopathy model, a method for manufacturing the same, and uses thereof. More specifically, the present invention relates to a use of a transgenic dog knocked out of a dystrophin gene as a disease animal model. 본 발명은 디스트로핀병증 모델용 형질전환 개 및...

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Hauptverfasser: LEE SEOK HEE, OH HYUN JU, CHUNG EUGENE, KIM MING JUNG, KIM JIN SOO, KIM GEON A, LEE BYEONG CHUN
Format: Patent
Sprache:eng ; kor
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