CRISPR/Cas9 Generation of canine dystrophinopathy model by nuclear transfer using CRISPR/Cas9-mediated somatic cells and th Use thereof
The present invention relates to a transgenic dog for a dystrophinopathy model, a method for manufacturing the same, and uses thereof. More specifically, the present invention relates to a use of a transgenic dog knocked out of a dystrophin gene as a disease animal model. 본 발명은 디스트로핀병증 모델용 형질전환 개 및...
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| creator | LEE SEOK HEE OH HYUN JU CHUNG EUGENE KIM MING JUNG KIM JIN SOO KIM GEON A LEE BYEONG CHUN |
| description | The present invention relates to a transgenic dog for a dystrophinopathy model, a method for manufacturing the same, and uses thereof. More specifically, the present invention relates to a use of a transgenic dog knocked out of a dystrophin gene as a disease animal model.
본 발명은 디스트로핀병증 모델용 형질전환 개 및 이의 제조방법, 그리고 이의 이용에 관한 것으로, 보다 구체적으로는 Dystrophin 유전자를 넉아웃(knock-out) 시킨 형질전환 개를 질환 동물 모델로 이용하는 것에 관한 것이다. |
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본 발명은 디스트로핀병증 모델용 형질전환 개 및 이의 제조방법, 그리고 이의 이용에 관한 것으로, 보다 구체적으로는 Dystrophin 유전자를 넉아웃(knock-out) 시킨 형질전환 개를 질환 동물 모델로 이용하는 것에 관한 것이다.</description><language>eng ; kor</language><subject>AGRICULTURE ; ANIMAL HUSBANDRY ; BEER ; BIOCHEMISTRY ; CARE OF BIRDS, FISHES, INSECTS ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FISHING ; FORESTRY ; HUMAN NECESSITIES ; HUNTING ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NEW BREEDS OF ANIMALS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR ; SPIRITS ; TRAPPING ; VINEGAR ; WINE</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210215&DB=EPODOC&CC=KR&NR=20210016170A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210215&DB=EPODOC&CC=KR&NR=20210016170A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEE SEOK HEE</creatorcontrib><creatorcontrib>OH HYUN JU</creatorcontrib><creatorcontrib>CHUNG EUGENE</creatorcontrib><creatorcontrib>KIM MING JUNG</creatorcontrib><creatorcontrib>KIM JIN SOO</creatorcontrib><creatorcontrib>KIM GEON A</creatorcontrib><creatorcontrib>LEE BYEONG CHUN</creatorcontrib><title>CRISPR/Cas9 Generation of canine dystrophinopathy model by nuclear transfer using CRISPR/Cas9-mediated somatic cells and th Use thereof</title><description>The present invention relates to a transgenic dog for a dystrophinopathy model, a method for manufacturing the same, and uses thereof. More specifically, the present invention relates to a use of a transgenic dog knocked out of a dystrophin gene as a disease animal model.
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본 발명은 디스트로핀병증 모델용 형질전환 개 및 이의 제조방법, 그리고 이의 이용에 관한 것으로, 보다 구체적으로는 Dystrophin 유전자를 넉아웃(knock-out) 시킨 형질전환 개를 질환 동물 모델로 이용하는 것에 관한 것이다.</abstract><oa>free_for_read</oa></addata></record> |
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| language | eng ; kor |
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| subjects | AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS TRAPPING VINEGAR WINE |
| title | CRISPR/Cas9 Generation of canine dystrophinopathy model by nuclear transfer using CRISPR/Cas9-mediated somatic cells and th Use thereof |
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