Prodrug compounds of monomethyl fumarate and their pharmaceutical compositions

The present invention provides: novel compounds capable of producing monomethyl fumarate after the compounds are administered; pharmaceutical compositions comprising the same as active ingredients; and pharmaceutical uses thereof for treating or alleviating various diseases including immune system a...

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Hauptverfasser: SON YEON WOO, KIM JAE SUN, LIM JEE WOONG, RYU HYUNG CHUL
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creator SON YEON WOO
KIM JAE SUN
LIM JEE WOONG
RYU HYUNG CHUL
description The present invention provides: novel compounds capable of producing monomethyl fumarate after the compounds are administered; pharmaceutical compositions comprising the same as active ingredients; and pharmaceutical uses thereof for treating or alleviating various diseases including immune system abnormalities, neurodegeneration, and/or inflammatory diseases. The compounds are represented by chemical formula 1. 본 발명은 투여 후 모노메틸 푸마레이트 (monomethyl fumarate)를 생성할 수 있는 신규 화합물, 이들을 유효성분으로 포함하는 약학 조성물, 이들의 면역체계 이상, 신경퇴행 및/또는 염증성 질환을 포함하는 다양한 질환의 치료 또는 개선 의약 용도를 제공한다.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Prodrug compounds of monomethyl fumarate and their pharmaceutical compositions
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