Prodrug compounds of monomethyl fumarate and their pharmaceutical compositions

The present invention provides: novel compounds capable of producing monomethyl fumarate after the compounds are administered; pharmaceutical compositions comprising the same as active ingredients; and pharmaceutical uses thereof for treating or alleviating various diseases including immune system a...

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Bibliographische Detailangaben
Hauptverfasser:	SON YEON WOO, KIM JAE SUN, LIM JEE WOONG, RYU HYUNG CHUL
Format:	Patent
Sprache:	eng ; kor
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides: novel compounds capable of producing monomethyl fumarate after the compounds are administered; pharmaceutical compositions comprising the same as active ingredients; and pharmaceutical uses thereof for treating or alleviating various diseases including immune system abnormalities, neurodegeneration, and/or inflammatory diseases. The compounds are represented by chemical formula 1. 본 발명은 투여 후 모노메틸 푸마레이트 (monomethyl fumarate)를 생성할 수 있는 신규 화합물, 이들을 유효성분으로 포함하는 약학 조성물, 이들의 면역체계 이상, 신경퇴행 및/또는 염증성 질환을 포함하는 다양한 질환의 치료 또는 개선 의약 용도를 제공한다.