COMPOSITION FOR TREATING ALLEVIATING OR PREVENTING PAIN COMPRISING BUPLEURI RADIX EXTRACT OR ITS INGREDIENT

The present invention relates to a composition for treating, alleviating or preventing neuropathic pain, which contains at least one among a Bupleurum falcatum extract or a component thereof, saikosaponin or a pharmaceutically acceptable salt thereof as an active component. The composition according...

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Bibliographische Detailangaben
Hauptverfasser: LEE, GYEONG BEEN, KIM, PAN SOO, YANG, JUNG EUN, CHOI, YONG MUN, SONG, MYUNG JIN, KIM, JIN KYU, LEE, JONG SUK, NAM, YEON JU, KIM, WOO JUNG
Format: Patent
Sprache:eng ; kor
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Zusammenfassung:The present invention relates to a composition for treating, alleviating or preventing neuropathic pain, which contains at least one among a Bupleurum falcatum extract or a component thereof, saikosaponin or a pharmaceutically acceptable salt thereof as an active component. The composition according to the present invention has a very excellent treatment, prevention, and alleviation effect on neuropathic pain by inhibiting TRPA1 activity. 본 발명은 시호 추출물 또는 이의 성분, 사이코사포닌 또는 이의 약학적으로 허용가능한 염 중 하나 이상을 유효성분으로 함유하는, 신경병증 통증의 치료, 완화 또는 예방용 조성물에 관한 것이다. 본 발명에 따른 조성물은 TRPA1 활성을 억제함으로써 신경병증 통증에 대해 매우 뛰어난 치료, 예방 및 완화 효능을 갖는다.