COMPOSITION FOR INTERNAL USE AND METHOD OF PRODUCT THEREOF

The present invention is to provide a composition for internal use which improves solubility in intestines and is excellent in bioavailability. More specifically, the present invention relates to a composition for internal use which contains (A) roperamide hydrochloride, and at least one organic aci...

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Hauptverfasser: EBI TAKAYUKI, YAMAGUCHI TSUBASA
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creator EBI TAKAYUKI
YAMAGUCHI TSUBASA
description The present invention is to provide a composition for internal use which improves solubility in intestines and is excellent in bioavailability. More specifically, the present invention relates to a composition for internal use which contains (A) roperamide hydrochloride, and at least one organic acid selected from a group consisting of (B) malic acid, tartaric acid, adipic acid, fumaric acid, maleic acid, malonic acid, and citric acid. 본 발명은 장내에서의 용해성을 개선하고, 생물학적 이용능에 우수한 내복 조성물을 제공하는 것으로서, (A) 로페라미드염산염과, (B) 사과산, 주석산, 아디핀산, 푸마르산, 말레인산, 말론산 및 구연산으로부터 선택되는 1종 이상의 유기산을 함유하는 내복 조성물에 관한 것이다.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOSITION FOR INTERNAL USE AND METHOD OF PRODUCT THEREOF
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